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This page contains information for participants who would like to submit a Clinical Trials of Medicinal Products (CTIMPs) application via the Combined Ways of Working (CWoW) pilot. The pilot is now accepting applications from new sponsor organisations from January 2021. To express an interest, please email cwow@hra.nhs.uk.

PLEASE NOTE: Applications which are being submitted via the CWoW pilot must be submitted using a new part of Integrated Research Application System (IRAS) and therefore applications should not be started in the standard part of IRAS.

The pilot

The Combined Ways of Working (CWoW) pilot sees the HRA working closely with colleagues in the Medicines and Healthcare products Regulatory Agency (MHRA) and across the devolved administrations to develop a single application route and a coordinated ethics and regulatory review leading to a single UK decision on a clinical trial. For more information about the pilot see the Combined Ways of Working page.

Participating Research Ethics Committees

Only certain RECs are involved in this pilot, although the number involved continues to increase. 

The most up-to-date information about which RECs are taking part in the pilot and when they meet will always be included in the REC meeting schedule below.

Each REC meeting has a submission period within which applications must be submitted. Applications into the pilot must be received during the submission period for any chosen REC, otherwise the application will be allocated to the next available REC meeting. Please note the reservation of slots in advance is required to increase the chance of the meeting having availability.The most up-to-date information about which Research Ethics Committees (RECs) are taking part in the pilot and when they meet will always be included in the REC meeting schedule below.

Each REC meeting has a submission period within which applications must be submitted. Applications into the pilot must be received during the submission period for any chosen REC, otherwise the application will be allocated to the next available REC meeting. Please note the reservation of slots in advance is required to increase the chance of the meeting having availability.

Committees currently accepting CWoW applications

Please note, the below is a list of the submission and meeting dates but does not reflect slot availability. Please follow the reservation instructions set out in the sponsor instruction document.

REC name Submission open Submission closed Meeting date
Bristol Central 9 Jan 2020 15 Jan 2020 29 Jan 2021
Bristol Central 5 Feb 2021 12 Feb 2021 26 Feb 2021
Bristol Central 5 Mar 2021 12 Mar 2021 26 Mar 2021
London Westminster 5 Jan 2020 12 Jan 2020 26 Jan 2021
London Westminster 02 Feb 2021 09 Feb 2021 23 Feb 2021
London Westminster 09 Mar 2021 16 Mar 2021 30 Mar 2021
London Hampstead 20 Jan 2021 27 Jan 2021 10 Feb 2021
East of Scot REC2 12 Jan 2021 19 Jan 2021 02 Feb 2021
East of Scot REC 2 9 Feb 2021 16 Feb 2021 02 Mar 2021
West of Scot REC 1 12 Jan 2021 19 Jan 2021 02 Feb 2021
West of Scot REC 1 9 Feb 2021 16 Feb 2021 02 Mar 2021
Hampshire A 16 Feb 2021 23 Feb 2021 09 Mar 2021
Oxford A 15 Jan 2021 22 Jan 2021 05 Feb 2021
Oxford A 12 Feb 2021 19 Feb 2021 05 Mar 2021
Manchester Central 18 Jan 2021 25 Jan 2021 08 Feb 2021
Manchester Central 15 Feb 2021 22 Feb 2021 08 Mar 2021
North West- Haydock 19 Jan 2021 26 Jan 2021 09 Feb 2021
North West- Haydock 16 Feb 2021 23 Feb 2021 09 Mar 2021
Leeds East 11 Jan 2021 18 Jan 2021 01 Feb 2021
Leeds East 8 Feb 2021 15 Feb 2021 01 Mar 2021
Health and Social Care REC A 5 Jan 2021 12 Jan 2021 26 Jan 2021
Health and Social Care REC A 2 Feb 2021 09 Feb 2021 23 Feb 2021
Health and Social Care REC A 2 Mar 2021 09 Mar 2021 23 Mar 2021
Health and Social Care REC B 21 Jan 2021 28 Jan 2021 11 Feb 2021
Health and Social Care REC B 18 Feb 2021 25 Feb 2021 11 Mar 2021
North East York 15 Jan 2021 22 Jan 2021 5 Feb 2021
Berkshire B 19 Jan 2021 26 Jan 2021 09 Feb 2021
Cambridge and Herts 20 Jan 2021 27 Jan 2021 10 Feb 2021
Cambridge and Herts 17 Feb 2021 24 Feb 2021 10 Mar 2021
London Surrey Borders 28 Jan 2021 03 Feb 2021 17 Feb 2021
London Surrey Borders 25 Feb 2021 03 Mar 2021 17 Mar 2021
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