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The HRA and Medicines and Healthcare products Regulatory Agency (MHRA) have been exploring opportunities to improve the service being offered for the approval and ongoing management of Clinical Trials of Medicinal Products (CTIMPs).

We see increased assimilation as a positive step forward. With that in mind we've launched a combined ways of working pilot to test an integrated process.

The pilot is currently open to applications by prior agreement only, with the expectation that it will be opened up to all CTIMP applications as it develops. If you are interested in submitting an application into this pilot, please email cwow.admin@nhs.net and include ‘combined ways of working pilot’ in the subject line.

The pilot process requires a single CTIMP application dossier to be submitted for both the Clinical Trial Authorisation (CTA) and the Research Ethics Committee (REC) opinion. In England and Wales this will also incorporate HRA and HCRW Approval.

The process involves a single submission, combined communications to request any further information required and a single communication to confirm the final decision.   

Only certain RECs are involved in this pilot, although the number involved continues to increase. 

The most up-to-date information about which RECs are taking part in the pilot and when they meet will always be included in the REC meeting schedule below

Each REC meeting has a submission period within which applications must be submitted. Applications into the pilot must be received during the submission period for any chosen REC, otherwise the application will be allocated to the next available REC meeting. 

Please note the reservation of slots in advance is required to increase the chance of the meeting having availability.

REC name Submission open Submission closed Meeting date
Bristol Central 05 Jan 2019 11 Jan 2019 25 Jan 2019
02 Feb 2019 08 Feb 2019 22 Feb 2019
09 Mar 2019 15 Mar 2019 29 Mar 2019
5 April 2019 12 Apr 2019 26 Apr 2019
10 May 2019 17 May 2019 31 May 2019
Camb and Herts 24 Jan 2019 30 Jan 2019 13 Feb 2019
21 Feb 2019 27 Feb 2019 13 Mar 2019
20 Mar 2019 27 Mar 2019 10 Apr 2019
17 Apr 2019 24 Apr 2019 08 May 2019
West of Scotland REC 1 16 Jan 2019 22 Jan 2019 05 Feb 2019
13 Feb 2019 19 Feb 2019 05 Mar 2019
12 Mar 2019 19 Mar 2019 02 Apr 2019
17 Apr 2019 24 Apr 2019 07 May 2019
London Hampstead 24 Jan 2019 30 Jan 2019 13 Feb 2019
20 Mar 2019 27 Mar 2019 10 Apr 2019
17 Apr 2019 24 Apr 2019 08 May 2019
Manchester Central 22 Dec 2018 28 Dec 2018 14 Jan 2019
19 Feb 2019 25 Feb 2019 11 Mar 2019
18 Mar 2019 25 Mar 2019 08 Apr 2019
22 Apr 2019 29 Apr 2019 13 May 2019
North West- Haydock 23 Jan 2019 29 Jan 2019 12 Feb 2019
20 Feb 2019 26 Feb 2019 12 Mar 2019
19 Mar 2019 26 Mar 2019 09 Apr 2019
23 Apr 2019 30 Apr 2019 14 May 2019
Leeds East 15 Jan 2019 22 Jan 2019 05 Feb 2019
13 Feb 2019 19 Feb 2019 05 Mar 2019
11 Mar 2019 18 Mar 2019 04 Apr 2019
22 Apr 2019 29 Apr 2019 14 May 2019
31 Jan 2019 06 Feb 2019 20 Feb 2019
28 Feb 2019 06 Mar 2019 20 Mar 2019
27 Mar 2019 03 Apr 2019 17 Apr 2019
29 Mar 2019 01 Apr 2019 15 May 2019
Health and Social Care REC A 09 Jan 2019 15 Jan 2019 29 Jan 2019
07 Feb 2019 12 Feb 2019 26 Feb 2019
06 Mar 2019 12 Mar 2019 26 Mar 2019
09 Apr 2019 16 Apr 2019 30 Apr 2019
25 Jan 2019 31 Jan 2019 14 Feb 2019
22 Feb 2019 28 Feb 2019 14 Mar 2019
21 Mar 2019 28 Mar 2019 11 Apr 2019
17 Apr 2019 24 Apr 2019 09 May 2019
North East -York REC 11 Jan 2019 18 Jan 2019 01 Feb 2019
15 Mar 2019 22 Mar 2019 05 Apr 2019
17 May 2019 24 May 2019 07 Jun 2019
14 Jun 2019 21 Jun 2019 05 Jul 2019
12 Jul 2019 19 Jul 2019 02 Aug 2019
20 Sep 2019 27 Sep 2019 11 Oct 2019
11 Oct 2019 18 Oct 2019 01 Nov 2019
15 Nov 2019 22 Nov 2019 06 Dec 2019
13 Dec 2019 20 Dec 2019 03 Jan 2019
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