Wrist Worn Trackers for monitoring activity in brain tumour patients
Research type
Research Study
Full title
Wrist worn trackers to monitor physical activity data in patients with primary and metastatic brain tumours. A Phase II feasibility study.
IRAS ID
236115
Contact name
Matthew Williams
Contact email
Sponsor organisation
Imperial College London
Duration of Study in the UK
4 years, 0 months, 0 days
Research summary
Most patient with brain tumours develop functional disturbance (weakness, balance problems, etc.) as part of their illness, and report fatigue as being a significant effect of the tumour and/or treatments. However, we have little detailed information of the impact of treatment on patient activity levels, nor how this relates to accepted measures of QoL and toxicity of treatment.\nWe aim to use patient-worn devices to better measure changes in activity levels as part of acute treatment-related toxicity and also monitor patients for signs of functional decline, with the intention of then being able to offer second-line\ntreatment sooner. However, in order to achieve these we need to understand normal changes in activity over time as patients undergo treatment.\nRecent developments in technology allow us the opportunity to gather high-resolution electronic data directly from the patient, using patient-worn wristband devices. These will allow us to monitor patient activity, and we will then examine the correlation between absolute levels and changes in patient activity levels with conventional measures of toxicity, HRQoL and disease progression/response.\nPrevious work has used patient-worn sensors to assess activity and gait in patients who have had strokes, and in those with multiple myeloma, and we have experience of using patient-worn electronic sensors in patients undergoing bariatric surgery. This is the first study in the world to assess the use of patient worn accelerometers in patients with brain tumours undergoing oncological treatments and follow up. We will also assess physical activity in matched healthy volunteer’s (main caregiver) to correlate any changes, and allow us to compare physical activity patterns.
REC name
South West - Cornwall & Plymouth Research Ethics Committee
REC reference
18/SW/0136
Date of REC Opinion
27 Jun 2018
REC opinion
Further Information Favourable Opinion