Wounds swabs to manage chronic wounds
Research type
Research Study
Full title
A clinical evaluation of using WOUNDCHEK Protease Status and WOUNDCHEK Bacterial Status wound swabs to manage chronic wounds: A Prospective Randomised Clinical Trial
IRAS ID
226102
Contact name
Ash Mosahebi
Contact email
Sponsor organisation
University College London
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Chronic wounds cause a significant burden to the economy of the NHS. Patient's quality life is often affected by chronic wounds due to the physical discomfort and emotional effects. In chronic wounds it is sometimes hard to determine when bacterial bio-burden is affected healing and requires intervention.
Bacterial protease are virulent factors that allow detection of bacteria in wounds behaving in a pathogenic mode often before an overt infection is apparent from clinical signs and symptoms. WOUNDCHEK™ Bacterial Status and WOUNDCHEK™ EPA wound swab provides a qualitative assessment of bacteria and bacterial protease activity in the wound. The detection will allow for earlier intervention to prevent a wound progressing to a more elevated infection status.
This study aims to determine whether the use of WOUNDCHEK Bacterial Status and WOUNDCHEK Protease Status in patients with chronic wounds and will inform future management and thus improve healing rates. We will compare monitoring chronic wounds at Watford Hospital with standard care against diagnostic testing for bacterial status and protease status in a randomised clinical trial.
REC name
London - Brent Research Ethics Committee
REC reference
18/LO/1856
Date of REC Opinion
21 Dec 2018
REC opinion
Further Information Favourable Opinion