WISE Study

  • Research type

    Research Study

  • Full title

    Whole Body Magnetic Resonance Imaging Study

  • IRAS ID

    254830

  • Contact name

    Dow-Mu Koh

  • Contact email

    Mu.Koh@icr.ac.uk

  • Sponsor organisation

    The Royal Marsden NHS Foundation Trust

  • Duration of Study in the UK

    0 years, 9 months, 29 days

  • Research summary

    In prostate cancer bone is the most common site for cancer spread, causing pain, fractures, nerve compression and death.
    New therapies are available for treating bone disease from cancer and this means that by maintaining patients on drugs that are effective and switching patients to other drugs when current treatment becomes ineffective, patients can be maintained ‘better for longer'. However, to do this, it is necessary to accurately tell whether a given treatment is working or not.
    In this study, we will perform whole body MRI scans, which include a special scan called diffusion-weighted MRI (DWI MRI) that can provide more information about your extent of disease. We aim to show that this test is better than the standard tests of CT and bone scan currently used in the NHS to monitor bone disease. The information from this study will be used to test a special software so that the test may more widely benefit patients across the NHS in the future.

  • REC name

    East Midlands - Leicester Central Research Ethics Committee

  • REC reference

    19/EM/0176

  • Date of REC Opinion

    14 Aug 2019

  • REC opinion

    Further Information Favourable Opinion