Wisdom Enhancement to Augment CBT for Post-Stroke Depression

  • Research type

    Research Study

  • Full title

    A Single Case Experiment Design Investigating Wisdom Enhancement to Augment CBT Outcomes for Depression in Post-Stroke Populations

  • IRAS ID

    335191

  • Contact name

    Ercan Hassan

  • Contact email

    nue22cyu@uea.ac.uk

  • Sponsor organisation

    UEA Research Sponsor

  • Clinicaltrials.gov Identifier

    NCT06451965

  • Duration of Study in the UK

    1 years, 7 months, 25 days

  • Research summary

    Research Summary:
    One-third of stroke survivors have post-stroke depression. Finding ways to help them feel more positive after such a challenging event can be tricky. Right now, there are no official guidelines on the best way to support post-stroke depression, and research into this is still growing. That is why we want to see if the wisdom enhancement timeline can improve the mood and overall well-being of people who have had a stroke.

    In this study, we have two goals. First, we want to see if the wisdom enhancement timeline technique can reduce depression in stroke survivors. Second, we aim to discover how this technique brings about positive mood changes.

    The main question we want to answer is whether using this technique can reduce feelings of depression in people who have had a stroke. We expect a positive change in how stroke survivors rate their mood before and after using the technique. We also expect that as their mood improves, other aspects, such as their sense of identity, self-esteem, and wisdom, will also improve.

    To carry out this study, we will work with nine stroke survivors receiving care from the National Health Service (NHS). By focusing on this smaller group, we hope to gain insights into the effectiveness of the technique in reducing depression and enhancing the lives of stroke survivors. This study is essential as it could help us understand the best way to support those with post-stroke depression.

    Lay summary of study results:
    All three participants showed improvements in wisdom first, followed by self-esteem and identity, with mood improving last.
    By the end of therapy, all participants felt more positive about themselves and were better able to engage in activities they had previously avoided.

    All participants showed clinically meaningful improvement in depression, meaning the changes were below the threshold for depression. Two participants showed reliable change, meaning the changes were strong enough to be considered meaningful.

    The intervention helped people reconnect with their sense of self, feel more confident, and develop a new perspective on their recovery.

  • REC name

    Yorkshire & The Humber - South Yorkshire Research Ethics Committee

  • REC reference

    24/YH/0055

  • Date of REC Opinion

    7 May 2024

  • REC opinion

    Further Information Favourable Opinion