WHiTE Four

• Research type

  Research Study

• Full title

  World Hip Trauma Evaluation Four: A randomised controlled trial of the sliding hip screw versus X-Bolt dynamic plating system for the fixation of trochanteric fractures of the hip.\n

• IRAS ID

  190802

• Contact name

  Xavier Griffin

• Contact email

  xavier.griffin@ndorms.ox.ac.uk

• ISRCTN Number

  ISRCTN92825709

• Duration of Study in the UK

  3 years, 2 months, 1 days

• Research summary

  Fractures of the proximal femur (hip fractures) are common, affecting almost 65,000 patients in England and Wales in 2013 and 1.31 million patients worldwide in 1990. Hip fractures constitute a heavy socioeconomic burden worldwide. The cost of this clinical problem is estimated at 1.75 million disability adjusted life years lost, 1.4% of the total healthcare burden in established market economies.\n\nTreatment with using the sliding hip screw (SHS) is well established in the treatment of extracapsular hip fractures. In the majority of simple fractures it is very effective at allowing controlling any movement of the fracture, leading to mechanical stability and subsequent fracture healing.\n\nHowever in some hip fractures the quality of the bone, due to severe thinning of the bones with age or osteoporosis, or the severity of the fracture means that the bone is deficient. This leads to the failure of the implant to control the movement of the fracture and consequent failure. Revision surgery, to either re­fix or replace the top of the hip bone is complex and the outcomes are poor in this frail group of patients. The X­Bolt dynamic plating system builds on the successful design features of the SHS but differs in the nature of the fixation in the hip. Expanding flanges are deployed to engage and compress the surrounding bone improving fixation.\n\nThe aim of this trial is to investigate the patients quality of life after a X­bolt dynamic plating system compared with the sliding hip screw in the treatment of trochanteric fractures of the hip.

• REC name

  West Midlands - Coventry & Warwickshire Research Ethics Committee

• REC reference

  16/WM/0001

• Date of REC Opinion

  5 Feb 2016

• REC opinion

  Favourable Opinion