West of Scotland Gastroenterology Researchers Tissue Bioresource

• Research type

  Research Tissue Bank

• IRAS ID

  319867

• Contact name

  Jonathan C Macdonald

• Contact email

  jonathan.macdonald@ggc.scot.nhs.uk

• Research summary

  West of Scotland Gastroenterology Researchers Tissue Bioresource

• REC name

  West of Scotland REC 4

• REC reference

  22/WS/0146

• Date of REC Opinion

  11 Nov 2022

• REC opinion

  Favourable Opinion

• Data collection arrangements

  We are developing a tissue resource which will include additional
  biopsies, and additional blood, urine and/or stool samples from patients to 
  support research activities of gastroenterology clinicians in NHS Greater Glasgow and Clyde, in collaboration with academic and industry partners. Where 
  appropriate patients may be requested to donate additional blood and/or biopsy 
  samples. The relevant Participant Information leaflets and Participant Consent 
  Forms for the extra tissues are included in this application.

  Additional tissue to be requested includes:

  Blood + derivatives (eg ­ whole blood, plasma, serum, buffy coat, ascitic fluid)
  Intestinal biopsy (taken at endoscopic procedure)
  Urine
  Faeces
  Saliva
  Hair follicle

  Additional tissue collected may be used directly in research projects or banked 
  for future use. 
  Material banked may be snap frozen and stored at low temperature or fixed and 
  stored as a formalin fixed paraffin block. Derivatives from the above may also 
  be used to produce DNA, protein and RNA extractions which may be stored for 
  research. 

  Tissue Micro Arrays (TMAs) may also be constructed from the tissue fixed paraffin block tissue resources.

• Research programme

  The NHS GG&C Biorepository has a fair and open access policy. Research  organisations that may request access to stored samples or request a new  collection include Universities, Research Institutions and commercial  organisations (e.g. Pharmaceutical and Biotech companies).  Applications for tissue from the NHS GG&C Gastroenterology Researchers Tissue Bioresource will be reviewed and authorised by the NHS GG&C Biorepository review panel with guidance where appropriate from the Gastroenterology Scientific Review Committee.

• RTBTitle

  West of Scotland Gastroenterology Researchers Tissue Bioresource

• Establishment organisation

  NHS Greater Glasgow & Clyde Biorepository

• Establishment organisation address

  Laboratory Medcine Building, Queen Elizabeth University Hospital

  1345 Govan Road

  Glasgow

  G51 4TY