Volatile organic compounds(VOCs) in diagnosis of bladder cancer
Research type
Research Study
Full title
Urinary volatile organic compounds (VOCs) in the diagnosis of urothelial bladder cancer
IRAS ID
179392
Contact name
Ghulam Nabi
Contact email
Sponsor organisation
University of Dundee
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
We hypothesise that the odours of bladder cancer patients' urine are different to healthy urine due to the changes of metabolic nature of cancerous tissue. We aim to generate fluorescent array pattern of volatile organic compounds from patients' urine samples. We can then compare and analyse to determine the relative contributions of specific volatile organic compounds within urine odour. Results will be compared to conventional histopathological examination of this tissue to determine the hallmark pattern of urine odour with cancer. Additionally, the same urine samples will be assessed by fluorescence spectroscopy to determine any correlation between urine fluorescence and presence of bladder cancer, and any correlation between urine fluorescence and presence of VOCs.
REC name
East of Scotland Research Ethics Service REC 1
REC reference
17/ES/0003
Date of REC Opinion
16 Feb 2017
REC opinion
Further Information Favourable Opinion