Volatile organic compounds(VOCs) in diagnosis of bladder cancer

• Research type

  Research Study

• Full title

  Urinary volatile organic compounds (VOCs) in the diagnosis of urothelial bladder cancer

• IRAS ID

  179392

• Contact name

  Ghulam Nabi

• Contact email

  g.nabi@dundee.ac.uk

• Sponsor organisation

  University of Dundee

• Duration of Study in the UK

  0 years, 11 months, 31 days

• Research summary

  We hypothesise that the odours of bladder cancer patients' urine are different to healthy urine due to the changes of metabolic nature of cancerous tissue. We aim to generate fluorescent array pattern of volatile organic compounds from patients' urine samples. We can then compare and analyse to determine the relative contributions of specific volatile organic compounds within urine odour. Results will be compared to conventional histopathological examination of this tissue to determine the hallmark pattern of urine odour with cancer. Additionally, the same urine samples will be assessed by fluorescence spectroscopy to determine any correlation between urine fluorescence and presence of bladder cancer, and any correlation between urine fluorescence and presence of VOCs.

• REC name

  East of Scotland Research Ethics Service REC 1

• REC reference

  17/ES/0003

• Date of REC Opinion

  16 Feb 2017

• REC opinion

  Further Information Favourable Opinion