VIRTAX-ADSP

  • Research type

    Research Study

  • Full title

    Effect of Virtual Reality and Trans Auricular X-Vagus nerve stimulation for Anxiety and Depression in chronic Shoulder Pain patients

  • IRAS ID

    346782

  • Contact name

    Athmaja Thottungal

  • Contact email

    athottungal@nhs.net

  • Sponsor organisation

    East Kent Hospitals University Foundation Trust

  • Duration of Study in the UK

    0 years, 9 months, 1 days

  • Research summary

    This study aims to evaluate the feasibility, safety, and preliminary efficacy of Vagus nerve stimulation (VNS) paired with virtual reality VR in reducing pain, enhancing psychological well-being, and improving quality of life for individuals with chronic shoulder pain awaiting surgery. It will provide critical insights into the potential of this combined intervention as a preoperative pain management strategy.
    Chronic shoulder pain is a debilitating condition that significantly impacts quality of life, daily functioning, and mental well-being. For individuals awaiting surgical intervention, prolonged pain often leads to heightened psychological distress, poor sleep quality, and reduced overall health outcomes. Innovative approaches are urgently needed to address these challenges and improve preoperative management.
    Vagus nerve stimulation (VNS) is an emerging, non-invasive therapy known to modulate pain perception and promote neuroplasticity, while virtual reality (VR) has demonstrated effectiveness in distracting from pain and improving psychological resilience. Combining these may offer a novel, multimodal approach to managing chronic pain by targeting both physical and psychological dimensions.

  • REC name

    East Midlands - Leicester Central Research Ethics Committee

  • REC reference

    25/EM/0207

  • Date of REC Opinion

    10 Oct 2025

  • REC opinion

    Further Information Favourable Opinion