VINDICATE-MI

• Research type

  Research Study

• Full title

  VItamin D as a Novel Determinant of Injurious Cardiac remodelling After acuTE Myocardial Infarction (VINDICATE-MI)

• IRAS ID

  223285

• Contact name

  Klaus Witte

• Contact email

  k.k.witte@leeds.ac.uk

• Sponsor organisation

  University of Leeds

• Duration of Study in the UK

  1 years, 11 months, 31 days

• Research summary

  We aim to explore whether there is a link between baseline vitamin D levels and changes in heart function in the six months following a heart attack.
  These changes, known as remodelling, are initially beneficial in helping the heart adapt and recover from the heart attack, but when unchecked become unhelpful, leading to heart dilation and eventually to heart failure. One previous study in the UK has described that vitamin D levels predict outcomes (major cardiac adverse events) following myocardial infarction. We want to see whether the vitamin D deficiency is related to changes in heart function following the heart attack and whether this relates to the worse outcomes (higher hospitalisation and mortality.

• REC name

  Yorkshire & The Humber - Leeds East Research Ethics Committee

• REC reference

  17/YH/0117

• Date of REC Opinion

  11 May 2017

• REC opinion

  Further Information Favourable Opinion