VEST

  • Research type

    Research Study

  • Full title

    VEST: The UK Vedolizumab real life experience study in inflammatory bowel disease

  • IRAS ID

    193055

  • Contact name

    JR Fraser Cummings

  • Contact email

    fraser.cummings@uhs.nhs.uk

  • Sponsor organisation

    University Hospital Southampton NHS Trust

  • Duration of Study in the UK

    2 years, 6 months, 1 days

  • Research summary

    Vedolizumab has been recently licensed for use in the management of ulcerative colitis (UC) and Crohn's disease (CD) and approved by NICE. However, there is a paucity of real life outcomes data currently to inform decisions about it's optimal use in clinical settings. This clinical observation study aims to capture the experience of this new therapy across the UK. Any hospital in the UK will be eligible to participate in the study and all adult patients treated with vedolizumab will be eligible for the study. Patients will complete a number of simple questionnaires whilst they have their vedolizumab infusions during their first year of treatment. Teams will record data such as details of the patient's IBD such as accurate characterisation of their disease, medications, previous history and blood tests that are taken part of the patients routine clinical data.

  • REC name

    London - Hampstead Research Ethics Committee

  • REC reference

    16/LO/0127

  • Date of REC Opinion

    21 Mar 2016

  • REC opinion

    Further Information Favourable Opinion