VERiTAS
Research type
Research Study
Full title
Venous thrombo Embolism Risk evaluation with Thromboelastometry Aided Stratification
IRAS ID
156262
Contact name
Amar Rangan
Contact email
Sponsor organisation
South Tees Hospitals NHS Trust
Research summary
Orthopaedic surgical procedures like hip fracture surgery or total hip or knee replacements carry a relatively high risk of causing a venous thromboembolism (VTE) which can cause dangerous blood clots to form in the vein. Hospitals routinely assess patients for risk of developing VTE and give medication to prevent this from happening. Despite this, a small proportion of patients still develop life threatening VTE. By studying blood from patients at various stages of their treatment using a state-of-the-art bleeding management machine called rotating thrombo-elastometry (ROTEM) it is hoped the research team will identify those most at risk and develop ways of minimising those risks.
ROTEM is a machine that helps surgical teams quickly identify the causes of excessive or acute bleeding but it has also been shown to identify potential blood clotting problems such as significant changes in the blood coagulation and platelet function.The aim of this study is to test the ability of ROTEM to detect persistent blood hypercoagulability in patients who receive pharmacological VTE prophylaxis following hip fracture surgery or total hip or knee replacement.
This study can help further knowledge and understanding of blood hyper coagulability in postoperative patients receiving pharmacological VTE prophylaxis which would increase health outcomes for future patients at risk of VTE and also lead to further reduction of morbidity and mortality from VTE while also offering significant savings to the NHS through better patient management.REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
14/NE/1107
Date of REC Opinion
30 Sep 2014
REC opinion
Favourable Opinion