Vascular Frailty - An observational cohort study
Research type
Research Study
Full title
A PILOT OBSERVATIONAL STUDY TO ASSESS THE EXTENT AND CONSEQUENCE OF FRAILTY AND ACTIVITY LEVELS IN PATIENTS UNDERGOING VASCULAR SURGERY
IRAS ID
239235
Contact name
Tristan Lane
Contact email
Sponsor organisation
Imperial College London and Imperial College Healthcare NHS Trust
Duration of Study in the UK
4 years, 0 months, 1 days
Research summary
Vascular surgical operations are major procedures with significant associated morbidity and mortality. Frailty is a major factor influencing surgical outcome, but the effect on morbidity/mortality and quality of life is poorly understood in vascular surgery. Activity levels play a significant role in frailty and in pre-intervention preparation. It is anticipated that as frailty levels increase, activity levels decrease. It is hypothesised that vascular surgery patients suffer from a high prevalence of frailty and that increasing frailty will lead to increased morbidity and mortality and decreased quality of life.
This initial study will provide the foundations to identify targets for improvement in degree of frailty, appropriateness for surgery and outcome.
This project aims to:
Assess and quantify the prevalence of frailty as well as recording activity levels in the vascular surgery patient cohort
Explore the impact of frailty and pre-op activity on surgical outcomes in the vascular surgical patient cohort to guide surgical treatments as well as future studies aimed at improving frailty and activity and thereby quality of life.
Identification of an appropriate metric of frailty for this population group to include activity, is a secondary aim of this proposal.Lay summary of study results: Due to time restrictions and the implications of COVID-19 on the vascular surgery service and its patients, the study was terminated before completing the required recruitment number.
REC name
London - Surrey Borders Research Ethics Committee
REC reference
18/LO/0497
Date of REC Opinion
28 Mar 2018
REC opinion
Favourable Opinion