Validation of the Lemann Index
Research type
Research Study
Full title
Validation of the Lemann Index:a Prospective, Cross-sectional, Multicenter, Observational, International Study
IRAS ID
231027
Contact name
Naila Arebi
Contact email
Sponsor organisation
London Northwest Healthcare NHS Trust
Duration of Study in the UK
0 years, 7 months, 31 days
Research summary
The aim of the study is to validate the Lemann index, the first tool assessing digestive damage in patients suffering from Crohn’s disease (CD). Crohn's disease is a chronic inflammatory gut disorder which can cause damage to the gut. Damage manifests as loss of function due to scarring or creation of tracts. Damage may require resection of parts of the gut. There is no collective measure of gut damage in Crohn's disease. We want study whether a scoring system called the Lemann index is a reliable measure of progressive damage in Crohn's disease. This is important because we want to be able to use this to study the effect of new drugs. All patients who have Crohn's disease and have undergone recent investigation are eligible. The study will be conducted in two NHS hospitals in the UK, several European and an American hospital. It is short study of <6 months. There is no intervention. We want to collect the results of the investigations that patients undergo and place specific readings into a chart to generate a Lemann index score.
REC name
East of Scotland Research Ethics Service REC 2
REC reference
17/ES/0106
Date of REC Opinion
2 Oct 2017
REC opinion
Further Information Favourable Opinion