Validation of Family Reported Outcome Measure (FROM-16)
Research type
Research Study
Full title
Validation of Family Reported Outcome Measure (FROM-16)
IRAS ID
281134
Contact name
Andrew Y Finlay
Contact email
Sponsor organisation
Cardiff University
Duration of Study in the UK
2 years, 5 months, 31 days
Research summary
The Family Reported Outcome Measure (FROM-16), created by our research team at Cardiff University in 2009-2014, is the first generic questionnaire designed to measure the impact of any chronic disease, across all medicine, on the quality of life (QoL) of family members or partners of patients with a health condition. The impact of having a person in a family with a disease on other family members is a major secondary burden of disease that has often in the past been ignored.
The FROM-16 is reliable, and several aspects of its validity have been demonstrated. The FROM-16 has shown high internal consistency, high reproducibility and construct validity.
Although initial validation of FROM-16 has been undertaken, further validation of the measure is necessary to enhance its usability across all disease areas of medicine including research/clinical trials, clinical practice; and to inform health economic evaluations of interventions. Further research will include the establishment of sensitivity to small but clinically important change over time; development of score interpretation bands; calculation of Minimal Important Difference (MID) and creation of formulae to convert FROM-16 scores to utility values.REC name
East of England - Cambridge East Research Ethics Committee
REC reference
20/EE/0242
Date of REC Opinion
23 Oct 2020
REC opinion
Further Information Favourable Opinion