Validation of a Parkinson's disease Rating Scale
Research type
Research Study
Full title
Validation of a Parkinson's disease Rating scale
IRAS ID
293664
Contact name
Anette Schrag
Contact email
Sponsor organisation
University College London
Clinicaltrials.gov Identifier
Z6364106/2024/10/15 health research , UCL Data Protection Registration number
Duration of Study in the UK
2 years, 10 months, 29 days
Research summary
The purpose of this study is to develop and evaluate the “Parkinson’s Disease Psychosis Rating Scale (PDP-RS)” together with other scales for Parkinson’s. The PDP-RS can be used to assess the severity of psychosis in patients with Parkinson’s. Psychosis means seeing or hearing things that are not there, having beliefs that things are happening they are not, or misperceptions such as seeing something that is there but looks like something else. Not all patients with Parkinson’s will develop psychosis. But, if they do, their doctor needs to know about it. It is not always possible to tell if a patient is having symptoms of psychosis just by looking at them or with the physical exam that your doctor performs. So, we need a way to help patients communicate with their doctors about these symptoms. We are therefore developing a rating scale to help describe the symptoms of psychosis in Parkinson’s and will evaluate them together with other scales in people with Parkinson’s. Participants will be invited to complete just one of the following study visits:
• Focus group: This will be a meeting where people with Parkinson's or care partners of people with Parkinson's will talk about symptoms such as those of psychosis.
OR
• Cognitive interview: The participant will review the developed version of the rating scale in an interview with open questions to get their opinion on the clarity of each item on the instrument and additional comments.
OR
• Validation: We will use the final version of the rating scale to assess participant's symptoms together with other scales and questionnaires.
These are sequential phases. The interviews will follow the focus groups and once this is completed we will follow with recruitment for the scale validation.
The participation may last between 1-2 hours.REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
25/NE/0042
Date of REC Opinion
28 Mar 2025
REC opinion
Further Information Favourable Opinion