Validating duplex scanning of the pedal vessels
Research type
Research Study
Full title
Validating duplex scanning of the pedal vessels by comparison with Digital subtraction Angiography (DSA).
IRAS ID
238584
Contact name
Emily Hillier
Contact email
Sponsor organisation
King's College Hospital
Duration of Study in the UK
0 years, 3 months, 1 days
Research summary
In this study, duplex (ultrasound) scanning of the arteries in the foot will be compared to another imaging modality. This other method is currently considered as the gold standard, which means it is considered to be the best way of imaging something, giving the most accurate results.\nThe other imaging method is DSA (Digital Subtraction Angiography). This involves the patient being injected with a contrast (dye) and an area of interest being imaged with x-ray to show which arteries have blood in them. \nIt is common in Diabetic patients with arterial disease to see blockages of the arteries in the calf, but open arteries in the foot. This means if a patient has blocked calf arteries, a bypass can be placed onto one of the arteries in the foot, allowing more blood flow to get to the foot, which can prevent amputation. \nIt is essential to have good imaging of these foot arteries in order to plan this type of surgery. This study is being carried out to investigate whether Duplex (ultrasound) scanning can give similar results to DSA.\nUltrasound scanning is non-invasive; the patient is not exposed to radiation and it does not require the use of contrast. Furthermore, a large number of diabetic patients also have poor kidney function and injecting the patient with the contrast used in DSA can cause their kidney function to decline.\nUsing ultrasound to image these arteries will be a safer and better option for this group of patients.\n
REC name
London - Bloomsbury Research Ethics Committee
REC reference
18/LO/0458
Date of REC Opinion
12 Mar 2018
REC opinion
Favourable Opinion