UTP Washout Study
Research type
Research Study
Full title
A Prospective Observational Study to Evaluate Participant Satisfaction and Quality of Life with Catheter Washout in Adults Living with Long-Term Catheters and Currently Using Uro-Tainer® Polihexanide 0.02% (UTP WASHOUT)
IRAS ID
356303
Contact name
Thomas Frei
Contact email
Sponsor organisation
B. Braun Medical AG
Clinicaltrials.gov Identifier
Duration of Study in the UK
0 years, 6 months, 18 days
Research summary
Several long-term catheter (LTC) washouts policies and maintenance solutions are used in clinical practice for prevention and/or management of LTC adverse events. Washouts used are of different types (normal saline, acidic, antimicrobial), and frequency of administration. The recent CATHETER II RCT showed potential benefit of a policy for prophylactic weekly catheter washout solutions (saline / acidic) in preventing blockages and catheter associated Urinary tract infections. However, the RCT was terminated early without reaching its target recruitment due to COVID pandemic [Abdel-fattah 2025].
In-addition to the mechanical benefit of washouts such as the saline, antimicrobial washout solutions aim to reduce or prevent bacterial growth and reduce LTC blockages [NHS 2013].
Uro-Tainer® Polihexanide 0.02% (acronym: UTP washout) is a sterile, single-use, water-based solution (100 ml) currently used in clinical practice in the UK (and Europe) for the irrigation of LTC. This maintenance solution for indwelling urethral and suprapubic LTC aim to aid removal of deposits, tissue waste, clots, and mucus.In this observational study of people living with LTC and currently using UTP washouts as part of their standard clinical care, we aim to address the following:
- Participant satisfaction with their UTP washout and Impact of their washout plan on their QoL
- Patient reported Adverse events (blockage, SCAUTI, others)
- Participant adherence to their current washout frequency plan
This is an observational study. The participants are those currently using UTP washouts as prescribed by their clinical care team. There will be no change in treatment for study purposes.REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
25/NE/0098
Date of REC Opinion
21 May 2025
REC opinion
Favourable Opinion