Utility of MRI for detection of inflammation in TTC
Research type
Research Study
Full title
Utility of T2* Magnetic Resonance Imaging for Detection of Inflammation in Acute Stress Induced (Tako-tsubo) Cardiomyopathy
IRAS ID
176850
Contact name
Dana Dawson
Contact email
Sponsor organisation
University of Aberdeen
Duration of Study in the UK
0 years, 8 months, 0 days
Research summary
Tako Tsubo Cardiomyopathy (TTC), also known as “Broken Heart Syndrome”, is disorder of the heart that occurs most commonly in women (although it occasionally occurs in men) and is usually related to a stressful event. Symptoms are often similar to a heart attack, and include chest pain and shortness of breath. Although TTC is not a new medical condition, it has not been widely recognised until the last decade. Currently we don’t have an exact understanding of how or why the heart is affected in this way, and so we are conducting a study to help us to understand what causes TTC. We aim to compare the signal intensity of MRI between healthy controls and patients with acute Tako-tsubo cardiomyopathy on the specific Philips 3T scanner that we use at our institution (the comparison with healthy volunteers is necessary because there is a small population of resident macrophages in the normal human heart).
REC name
East of Scotland Research Ethics Service REC 1
REC reference
15/ES/0041
Date of REC Opinion
1 Apr 2015
REC opinion
Further Information Favourable Opinion