UTI diagnosis in pregnancy by VOC analysis

  • Research type

    Research Study

  • Full title

    Point of care diagnosis of urinary tract infections (UTIs) in pregnancy by volatile organic compound (VOC) analysis

  • IRAS ID

    282829

  • Contact name

    Lauren Lacey

  • Contact email

    l.lacey.1@warwick.ac.uk

  • Sponsor organisation

    University of Warwick

  • Duration of Study in the UK

    3 years, months, 31 days

  • Research summary

    Urinary tract infections (UTIs) are common in pregnancy affecting up to one in ten women. Some of these women have symptoms to warn them but others do not. UTIs can lead to complications in pregnancy which can affect both the mother and the baby and therefore diagnosis in a timely fashion is important. The current rapid tests used in clinics are not very accurate to diagnose UTIs. Consequently, it is currently recommended that all women provide a urine sample when they book their pregnancy with their community midwife which is sent to the laboratory to be cultured. If bacteria grow additional tests are done to determine which antibiotics will be effective at treating that bacteria which has grown. This is a time consuming and expensive process which can lead to delays in starting treatment.
    A new technology which mimics the human nose has been recently shown to accurately diagnose several human diseases including various infections. We want to ascertain if this technology which could be available as a bedside test can diagnose UTIs in pregnancy.

  • REC name

    North West - Greater Manchester South Research Ethics Committee

  • REC reference

    20/NW/0450

  • Date of REC Opinion

    30 Mar 2021

  • REC opinion

    Further Information Favourable Opinion