Uterine Protection in Lynch Syndrome (UP study)

• Research type

  Research Study

• Full title

  Uterine Protection in Lynch Syndrome - An exploration of current risk reductive strategies and potential surveillance methodologies.

• IRAS ID

  194351

• Contact name

  Emma Crosbie

• Contact email

  emma.crosbie@manchester.ac.uk

• Sponsor organisation

  University of Manchester

• Duration of Study in the UK

  3 years, 0 months, 28 days

• Research summary

  This is an exploratory study with the aim of contributing pilot data
  1. Explore the current methods utilised by Lynch Syndrome women to reduce their risk of endometrial cancer
  2. Evaluate the impact of different risk reducing strategies on the incidence of endometrial cancer in Lynch Syndrome women.
  3. Investigate the reasons as to why Lynch Syndrome women engage with different risk reducing behaviours.
  4. Study the impact of known risk factors for endometrial cancer on Lynch Syndrome women
  5. Identify the different management strategies used by NHS services in England to reduce the risk of endometrial cancer in Lynch Syndrome.
  6. Evaluate the local service to explore the effectiveness of the different modalities of endometrial surveillance

• REC name

  London - West London & GTAC Research Ethics Committee

• REC reference

  16/LO/1788

• Date of REC Opinion

  6 Oct 2016

• REC opinion

  Further Information Favourable Opinion