Use of LiDCOplus in fluid resuscitation decision-making
Research type
Research Study
Full title
Does the use of LiDCOplus alter decision-making in fluid prescription during resuscitation in the intensive care unit.
IRAS ID
196092
Contact name
James Patterson
Contact email
Sponsor organisation
NHS GGC Clinical Research and Development Central Office
Duration of Study in the UK
0 years, 4 months, days
Research summary
Unwell patients in the intensive care unit (ICU) often need supplementary fluids to be given into the bloodstream through a drip in a vein (venous cannula), however too much fluid can be harmful. It can sometimes be difficult to tell whether or not a patient will benefit from extra fluids so they are given a "fluid challenge", whereby a small volume of fluid is given quickly into the cannula and the change in their status is noted. If the patient’s condition improves, this suggests that the patient is “fluid responsive” and needs more fluid.
A LiDCOplus cardiac output monitor is a device used in the ICU to estimate the amount of blood ejected from the heart on each heartbeat using pressure readings obtained from a tube placed in one of the patient's arteries (arterial line).
We aim to determine whether or not the use of this device called makes a difference to the judgement of “fluid responsiveness” when the patient is given a fluid challenge when compared to simply using measurements of pulse and blood pressure and assessing the circulation in the patient's limbs. This will allow us to determine whether or not the LiDCOplus cardiac output monitor alters the decisions made by doctors and nurses about how much fluid to give their patients and hence if it is of any benefit.REC name
West Midlands - Edgbaston Research Ethics Committee
REC reference
16/WM/0230
Date of REC Opinion
20 May 2016
REC opinion
Favourable Opinion