Use of H-FABP to confirm NSTEMI for chest pain patients

• Research type

  Research Study

• Full title

  A feasibility assessment of the potential use of the Heart Type Fatty Acid Binding Protein (H-FABP) cardiac biomarker to confirm Non-Segment Elevation Myocardial Infarction (NSTEMI) diagnosis in the pre-hospital setting of patients experiencing chest pain

• IRAS ID

  120828

• Contact name

  Peter Mason

• Contact email

  peter.mason@emas.nhs.uk

• Sponsor organisation

  East Midlands Ambulance Service NHS Trust

• Clinicaltrials.gov Identifier

  N/A, N/A

• Duration of Study in the UK

  0 years, 7 months, 31 days

• Research summary

  The overall aim is to identify a diagnosis tool that can support clinicians when making diagnosis of Myocardial Infarctions (MI), where an echocardiogram (ECG) returns a negative diagnosis.

  The objectives are:

  • To test whether H-FABP is a suitable substance to detect MI at an appropriate point in pre-hospital care to enable the use of cardiac pathways rather than the default use of Accident and Emergency (A&E)/Emergency Department (ED)
  • To test an H-FABP detection tool
  • To identify the appropriate combination of diagnosis tools to generate the correct diagnosis in the highest proportion of instances

• REC name

  North West - Haydock Research Ethics Committee

• REC reference

  15/NW/0352

• Date of REC Opinion

  11 Jun 2015

• REC opinion

  Further Information Favourable Opinion