Use of bacterial genomics to assess diabetic foot infection microbiota
Research type
Research Study
Full title
Use of bacterial Genomics to assess the AMR Diabetic Foot Infection microbiota
IRAS ID
299735
Contact name
David G Partridge
Contact email
Sponsor organisation
Sheffield Teaching Hospitals Foundation trust
Duration of Study in the UK
0 years, 0 months, 30 days
Research summary
Diabetes has been identified as risk factor for infection with antibiotic resistant pathogens. Current understanding of the pathogens that cause infections in diabetic patients is limited dues to the limits of current laboratory techniques used in the clinical setting. This research project will examine the bacterial species (microbiota) present during Diabetic Foot Infections (DFI). It is now understood that the range of species of bacteria present in DFI is complex and current standard culture techniques are not able to fully identify these. For this pilot project samples will be assessed by genetic sequence analysis to determine if sequencing methods identify a greater number of species than those in standard culture methods. The data generated from this project will be used to further develop the diagnostic pathway and potential of sequencing technology for diagnosis and management of these patients.
REC name
South Central - Berkshire Research Ethics Committee
REC reference
21/SC/0338
Date of REC Opinion
27 Sep 2021
REC opinion
Favourable Opinion