Understanding Treatment Adherence in Paediatric GHD
Research type
Research Study
Full title
Identifying Potentially Modifiable Factors associated with Treatment Non-Adherence in Paediatric Growth Hormone Deficiency
IRAS ID
244287
Contact name
John Weinman
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
0 years, 8 months, 0 days
Research summary
Despite the benefits of recombinant growth hormone treatment on long-term health outcomes, evidence has shown that, a large proportion of growth hormone deficient children under-perform in terms of achieving their target adult height. Such perceived failure has been largely attributed to treatment non-adherence. The key to understanding the complex and multifaceted issue of paediatric non-adherence to growth hormone treatment is to understand the parents’/guardians’ views and experiences of their child’s condition and treatment. Few studies however have explicitly examined parental perspectives and experiences within the area of Growth Hormone Deficiency and growth hormone treatment. This cross-sectional study has been devised to qualitatively (Study 1) and quantitatively (Study 2) explore and examine parent’s/guardian's personal beliefs, views and experiences of their child’s condition and treatment, in addition to their perceived relationship with the healthcare provider (HCP), to determine whether these may influence and inform the way in which their child's prescribed medication is used. An interview (Study 1) and self-report questionnaire (Study 2) will be administered to both naïve [<6 months] and established [>6 months] parents in three outpatient hospital clinics.
REC name
London - Surrey Borders Research Ethics Committee
REC reference
18/LO/1437
Date of REC Opinion
13 Aug 2018
REC opinion
Further Information Favourable Opinion