Understanding barriers and outcomes of unspecified (altruistic) kidney
Research type
Research Study
Full title
Understanding barriers and outcomes of unspecified (altruistic) kidney donation
IRAS ID
186383
Contact name
Nizam Mamode
Contact email
Sponsor organisation
Guy's and St Thomas' Foundation NHS Trust
Duration of Study in the UK
4 years, 11 months, 31 days
Research summary
The waiting list for a kidney transplant in the UK includes over 7000 people, and is increasing. The best available treatment for kidney failure is a kidney transplant from a living donor. The donor is usually a friend or relative. In 2006 donation to a stranger (referred to as unspecified altruistic donation) was introduced in the UK. Since then the number of unspecified altruistic donations has increased year on year. In 2012, 60 transplants used kidneys from unspecified altruistic donors, accounting for around 1 in 20 of all kidney transplants from living donors. These donations provide a high quality kidney to patients on the national transplant list and to someone in the paired/pooled scheme who would not otherwise obtain a transplant due to incompatibility with their donor.The number of unspecified altruistic donations varies widely across transplant centres. In 2012, three (out of a total of 23) centres accounted for 45% of all unspecified altruistic donations. There is considerable variation between centres in the proportion of people making contact in order to donate a kidney, who actually proceed to donation. Reasons for this variation are unknown but may include resource issues, concerns regarding an individual's motivations, or that the individual may develop physical or psychological issues after donation.
The aim of this project is to perform a comprehensive assessment of the unspecified altruistic donor programme in the UK to explore variation between centres, and identify barriers and facilitators to donation for those that have expressed a willingness to do so. These questions will be addressed by interviews and questionnaires sent to potential or actual unspecified donors in the UK.REC name
South Central - Berkshire B Research Ethics Committee
REC reference
15/SC/0637
Date of REC Opinion
27 Nov 2015
REC opinion
Further Information Favourable Opinion