UK Computer Aided Theragnostics (ukCAT)

  • Research type

    Research Database



  • Contact name

    Daniel JOHNSON

  • Contact email

  • Research summary

    UK Computer Aided Theragnostics (ukCAT)

  • REC name

    North East - Tyne & Wear South Research Ethics Committee

  • REC reference


  • Date of REC Opinion

    2 Nov 2018

  • REC opinion

    Favourable Opinion

  • Data collection arrangements

    The ukCAT system collects anonymous data about all patients, their disease and the outcome of treatment and uses
    this information to build computer models which, in the future, may potentially be used to predict outcomes for new
    patients. In addition to records of non-identifiable patient characterisics (e.g. age, gender, performance status),
    disease type (cancer type and stage) and treatments (surgery, chemotherapy, radiotherapy), the system also performs
    calculations on scan images including information such as tumour size and shape.
    A potential problem in creating computer models is that the amount of data used is too small or not representative of
    all patients. A way around this is to combine data from many different hospitals to ensure the amount of data is large
    and varied, resulting in higher quality models. However, anonymous medical information must be treated very carefully
    to ensure it remains secure. The CAT system allows models to use data from around the world without any data ever
    leaving the hospital where it is stored. The models comes to the data, data never leaves an institution.

  • Research programme

    Computer Aided Theragnostics (CAT) is the use of large population-based cancer patient data that aims to develop our understanding of patients, imaging and treatment characteristics linked to outcome (e.g. toxicity and survival). Ultimately the development of theragnostics will lead to the individualisation of treatment based on population data as opposed to selected patients included in clinical trials. However this tailored approach will have to be tested in prospective clinical trials and is not part of this application. One aim of the project will be to develop computer models linking outcome (survival, side effects) to individual patient characteristics, scan image results, markers in blood and tissue and treatment. The models learn from previously treated patients to provide individual predictions of the potential help and harm of a particular therapy for each new patient.

  • Research database title

    UK Computer Aided Theragnostics (ukCAT)

  • Establishment organisation

    South Tees Hospitals NHS FT

  • Establishment organisation address

    South Tees Institute of Learning, Research and Innovation

    Marton Road


    TS4 3BW