TYPPEX WP4

  • Research type

    Research Study

  • Full title

    Addressing common mental disorder and psychotic experiences: a stepped wedge cluster randomised trial with nested economic and process evaluation of a training package for CBT therapists in Improving Access to Psychological Therapies (IAPT) services.

  • IRAS ID

    275169

  • Contact name

    Jesus Perez

  • Contact email

    jesus.perez@cpft.nhs.uk

  • Sponsor organisation

    Cambridgeshire and Peterborough NHS Foundation Trust

  • ISRCTN Number

    ISRCTN93895792

  • Duration of Study in the UK

    3 years, 5 months, 30 days

  • Research summary

    The Improving Access to Psychological Therapy (IAPT) service treats nearly a million people annually. However, recovery rates are lower than anticipated, especially for people with common mental disorder including psychotic experiences, such as paranoia or voice hallucinations. This trial is part of the wider TYPPEX (Tailoring evidence-based psychological therapY for People with common mental disorder including Psychotic Experiences) programme, which aims to address the unmet need of service users who experience, but do not necessarily disclose, psychotic phenomena.
    The trial will recruit eight teams of 8-10 therapists within the IAPT service, across three mental health Trusts. After a control period across all teams, two teams will be randomised to receive TYPPEX training, then a further two teams, and so on, until all teams have received the intervention. This is referred to as a stepped-wedge trial design, where each “step” is six months in length.
    The training package will support therapists to deliver care to service users with psychotic experiences and common mental disorder; people who have scored above a threshold on the Community Assessment of Psychic Experiences (CAPE) questionnaire, referred to as CAPE+.
    Routine clinical data for all CAPE-assessed service users will be provided by the Trusts to the Norwich Clinical Trials Unit in a pseudonymised form. The trial will test the hypothesis that care delivered to CAPE+ IAPT users by TYPPEX-trained therapists will be more effective and cost-effective than treatment-as-usual in IAPT services.
    A sub-set of 300 CAPE+ service users will be asked to consent to the collection of health economic data via questionnaires at baseline (therapy session 2), then at 3, 6, 9 and 12 months after that. A nested process evaluation will explore stakeholders’ experiences of TYPPEX via interviews.

  • REC name

    South Central - Berkshire Research Ethics Committee

  • REC reference

    20/SC/0135

  • Date of REC Opinion

    28 Apr 2020

  • REC opinion

    Favourable Opinion