Turning6
Research type
Research Study
Full title
Turning6 - A Clinical and Neurodevelopmental follow up of EPIPEG participants at 60 months
IRAS ID
304070
Contact name
Helen Cross
Contact email
Sponsor organisation
Young Epilepsy
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Children who develop epilepsy as babies often have significant learning and behavioural problems and seizures which are difficult to control. They rarely progress at the same rate as their peers in school, and their life chances are significantly diminished. These early-onset epilepsies are hard to diagnose and equally hard to determine how well treatment will work. Many of these children remain without a specific diagnosis. This can be distressing for parents and worrying for doctors. Epilepsy affects every aspect of a child’s life and evidence shows that early intervention is key to improving outcomes in each area. This project aims to determine predictors of outcome in children with early onset epilepsy, ultimately improving treatment and outcomes in relation to their overall health and development, quality of life and life opportunities. We will follow 119 children, who we saw as babies, as they grow up to gain a unique understanding of the early onset epilepsies. We will assess their clinical and developmental progress alongside their genetics and brain imaging. This will allow us to determine what predictors of outcome can be used by doctors. We envisage this data being published and of benefit to patients in the short to medium term.
REC name
London - Surrey Borders Research Ethics Committee
REC reference
22/PR/0229
Date of REC Opinion
19 May 2022
REC opinion
Further Information Favourable Opinion