Troponin T Haemolysis Study
Research type
Research Study
Full title
Investigation in to the effect of in vitro haemolysis on serum High sensitivity Troponin T measurements from patients presenting in A&E.
IRAS ID
228202
Contact name
Amanda Hawkins
Contact email
Sponsor organisation
Poole Hospital NHS Foundation trust
Clinicaltrials.gov Identifier
Pending, Clinicaltrials.gov
Duration of Study in the UK
0 years, 2 months, 26 days
Research summary
This study will be investigating how a common blood test for identifying heart damage (Troponin T) is affected by red blood cell damage in the blood sample (Haemolysis). It is already known that damage to the red blood cells during or after blood sample collection can cause falsely low test results however the exact amount is not clear. Some previous studies suggest that a much higher amount of red blood cell damage could be allowable when reporting the test results.
This study will mimic the type of red blood cell damage that occurs in the hospital and determine what degree of damage or 'haemolysis' causes a significant reduction in the test result and therefore determine an allowable limit for safely reporting the test result.
The results of this study may help provide an evidence based approach to improving current practice and may lead to less rejected blood samples, fewer repeat tests, improved A&E treatment times, general cost savings and an improved service to patients.REC name
London - Camberwell St Giles Research Ethics Committee
REC reference
17/LO/1371
Date of REC Opinion
18 Aug 2017
REC opinion
Further Information Favourable Opinion