Trial recruitment for an imaging study of bone and joint health
Research type
Research Study
Full title
Trial recruitment of adults aged 20 - 44 for an imaging study of bone and joint health
IRAS ID
209255
Contact name
Jennifer Gregory
Contact email
Sponsor organisation
University of Aberdeen
Duration of Study in the UK
0 years, 6 months, 0 days
Research summary
The aim of our main study is to develop a clinical tool, describing joint shape, for the assessment of musculoskeletal morbidity, especially osteoarthritis, osteoporosis and low back pain using Dual energy X-ray Absorptiometry (DXA) images collected by the UK Biobank. UK Biobank is a national health resource of data collected from people aged 40-69, created with the aim of improving the prevention, diagnosis and treatment of a wide range of serious and life-threatening diseases. To allow us to develop our clinical tool to fully describe joint shape as a function of age and sex we plan to augment the Biobank data by recruiting individuals aged 20-44. Because of work and family commitments, this age-range is recognised to be hard to involve in studies but is essential to augment the data from UK Biobank we intend to use for the main study.\nThis pilot study will test our proposed recruitment strategy for this younger aged group. We will recruit 40 individuals from two working-age groups, 20-34 and 35-44 years for measurement of the shape of their hips, knees and lumbar spines using DXA. Individuals will be identified and initially contacted by the team at SHARE and, if they wish to take part, their details will be passed to our research team. The proposed pilot study will test how best to contact individuals (letter or electronic), the response rate we might expect, what flexibility may be needed in making appointments and the numbers required for a power calculation for the larger study. Participants will be invited to attend for DXA scans of their hips, knees, spines and whole body at the Foresterhill DXA facility.\n
REC name
North West - Preston Research Ethics Committee
REC reference
16/NW/0666
Date of REC Opinion
14 Sep 2016
REC opinion
Favourable Opinion