Treatment Pathways and Healthcare Resource Use in Mantle Cell Lymphoma

  • Research type

    Research Study

  • Full title

    The THRUM Study - Treatment Pathways, Healthcare Resource Use and Clinical outcomes of Patients with Mantle Cell Lymphoma in England

  • IRAS ID

    272752

  • Contact name

    Adrian Paul Rabe

  • Contact email

    arabe@healthiq.co.uk

  • Sponsor organisation

    Health IQ

  • Duration of Study in the UK

    1 years, 0 months, 0 days

  • Research summary

    Mantle cell lymphoma is a cancer involving specific types of white blood cells. Normal white blood cells function to protect the body as part of the immune system. In mantle cell lymphoma, these cells have mutated and now invade and harm different parts of the body. Being a very debilitating disease, it is important to understand how much resources they use up in the national health service, as well as the
    various treatments they undergo, and how those treatments impact their survival. This study aims to use anonymized and pseudonymized data from Public Health England to construct a group of patients with advanced melanoma. Using the same dataset linked to secondary care and to the cancer treatment dataset, the study would determine healthcare resource use and treatment pathways, as well as clinical outcomes. The span of time covered would be from 2010 to the latest available
    data when it would be requested. Once completed, this study would hopefully inform health policy to reduce healthcare resources and reconfigure services to provide better treatment pathways for patients.

  • REC name

    East Midlands - Nottingham 1 Research Ethics Committee

  • REC reference

    19/EM/0307

  • Date of REC Opinion

    21 Oct 2019

  • REC opinion

    Favourable Opinion