Treatment Adherence in Paediatric GHD: A Feasibility Study v1
Research type
Research Study
Full title
Understanding and Improving Treatment Adherence in Paediatric Growth Hormone Deficiency: A Feasibility Study.
IRAS ID
261828
Contact name
John Weinman
Contact email
Duration of Study in the UK
0 years, 9 months, 30 days
Research summary
Despite the benefits of growth hormone treatment on long-term clinical health outcomes, evidence has shown that many children with Growth Hormone Deficiency still do not achieve their target genetic adult height. These suboptimal outcomes have been largely attributed to treatment non-adherence. A recent systematic review has found that up to 71% of growth hormone deficient patients/families are non-adherent to treatment as prescribed, which as a result, has a substantial impact upon clinical health outcomes and the wider healthcare system.
The aim of the current study is to test and evaluate the feasibility and acceptability of a brief adherence screener intervention, designed to improve the use of prescribed growth hormone treatment within endocrine clinical practice. An pre-test to post-test feasibility study design will be conducted. Initial observations of paediatric clinical nurse specialists routine consultations will be conducted to observe standard care within endocrine clinical practice. Following the delivery of an intervention training session(s), the paediatric clinical nurse specialists will be observed within their consultations using the brief adherence screener and training manual.
Observations will investigate how easily the new intervention can be used to identify, discuss and address treatment adherence barriers within routine clinical care. Parent/caregiver questionnaires and paediatric clinical nurse specialist interviews will be conducted to gain feedback on the experiences and satisfaction of using a Brief Screener Adherence Intervention within routine consultations.
REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
20/NE/0035
Date of REC Opinion
5 Mar 2020
REC opinion
Further Information Favourable Opinion