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Translating Epidemiology to Screening for Trypanosoma cruzi (TEST)

  • Research type

    Research Study

  • Full title

    Translating Epidemiology to Screening for Trypanosoma cruzi (TEST)



  • Contact name

    Natalie Elkheir

  • Contact email

  • Sponsor organisation

    London School of Hygiene & Tropical Medicine

  • Duration of Study in the UK

    1 years, 5 months, 31 days

  • Research summary

    Chagas disease is caused by a parasite, called Trypanosoma cruzi, which is mainly spread by bugs in Latin America (South America, Central America and Mexico). It can also be spread from mothers to their babies during pregnancy, as well as through eating contaminated foods, blood transfusions and organ transplants. The parasite can stay silent, without causing any symptoms, for many years before it causes heart and gut problems in about one third of infected individuals. We have a large number of people from Latin America living in London, who may be infected with the parasite. We don't know how many people are infected in London, nor how many of those are likely to develop complications from the disease. This study will offer one-off screening blood tests for Chagas disease to people from Latin America at their GP surgeries, in hospital and in community centres outside traditional healthcare services. To understand more about who's at risk, we will also ask people some basic questions about who they are where they have lived in a short online questionnaire. This study will allow us to better understand how Chagas disease affects migrants in London and to design a screening programme accordingly.

  • REC name

    London - City & East Research Ethics Committee

  • REC reference


  • Date of REC Opinion

    8 Feb 2023

  • REC opinion

    Favourable Opinion

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