Transconjunctival vs transcutaneous anaesthesia in oculoplastics
Research type
Research Study
Full title
Comparative study of transconjunctival vs. transcutaneous routes for administration of local anaesthesia in oculoplastic surgery
IRAS ID
256690
Contact name
We Fong Siah
Contact email
Sponsor organisation
University Hospitals Southampton NHS Foundation Trust
Clinicaltrials.gov Identifier
Duration of Study in the UK
0 years, 4 months, 1 days
Research summary
Eyelid surgery is commonly performed under local anaesthesia. For many such procedures, the local anaesthetic injection may be given either transcutaneously (through the skin) or transconjunctivally (through the conjunctiva, i.e. from the inner surface of the eyelid after administration of topical anaesthetic drops). Both methods are commonly used, sometimes in combination. Currently, the choice of route is largely determined by surgeon preference, but it is not known whether one method is better or more comfortable than the other. Our study will compare the two methods of local anaesthetic administration, in terms of patient comfort during anaesthetic administration, efficacy (i.e. whether any additional anaesthetic is needed during surgery), and adverse effects (e.g. bruising, postoperative double vision).\n\nWe will recruit adult patients who are due to undergo eyelid surgery on both sides under local anaesthesia, on Miss Siah’s lists at Southampton General Hospital or Lymington Hospital. Patients will receive topical anaesthetic eye drops to both eyes, followed by an injection of local anaesthetic to each eyelid. One side will be administered transcutaneously, and the other side transconjunctivally. The order be randomised. After the injections, participants will be asked to rate their pain levels during each injection on a standardised numerical scale (1-10). A photograph will also be taken, so that an independent assessor can subsequently rate the extent of any bruising. The eyelid surgery will then be performed as normal, with any need for further anaesthetic during the surgery being recorded. Patients will attend for their normal follow-up appointment afterwards and any postoperative complications will be recorded, but the study will not require any extra hospital visits. The study is sponsored by University Hospitals NHS Foundation Trust, but does not have any external funding.
REC name
Yorkshire & The Humber - Leeds East Research Ethics Committee
REC reference
19/YH/0144
Date of REC Opinion
30 Apr 2019
REC opinion
Favourable Opinion