TRAITS-HFpEF
Research type
Research Study
Full title
Characteristics, phenotypes and traits of heart failure with preserved ejection fraction
IRAS ID
218524
Contact name
Christopher Miller
Contact email
Sponsor organisation
University Hospital of South Manchester NHS Foundation Trust
Duration of Study in the UK
20 years, 2 months, 1 days
Research summary
Heart failure with preserved ejection fraction (HFpEF) accounts for half the number of patients with heart failure, causing significant morbidity and mortality. Unlike heart failure with reduced ejection fraction, there are currently no evidence based treatments that have been shown to improve survival, however there are interventions that have been shown to reduce symptoms by improving exercise intolerance and preventing hospital admission. Diagnosis can be complex due to the heterogeneity seen in patients presenting with variable symptoms attributed to heart failure. The National Institute for Health and Care Excellence recommends that all patients with suspected heart failure be seen by a clinician with a specialist interest in heart failure. For this reason, University Hospital of South Manchester (UHSM) are providing a dedicated outpatient service to see patients with suspected or worsening HFpEF, aimed at clarifying clinical diagnosis and providing optimal evidence based treatment and support.
This study aims to collect data on this cohort of patients who attend a dedicated outpatient HFpEF clinic. The study aims to provide insights into the epidemiology, co-morbidities, clinical parameters, investigational results including blood tests and cardiac imaging, and the short and long-term prognosis of patients with HFpEF. It will also provide information on the patient population attending a dedicated NHS outpatient HFpEF clinic with the intention to provide information on the functioning of such a service and how this is used to meet patient needs.
REC name
London - Brent Research Ethics Committee
REC reference
17/LO/0154
Date of REC Opinion
21 Feb 2017
REC opinion
Further Information Favourable Opinion