Tracking physical activity after total knee arthroplasty v1.0
Research type
Research Study
Full title
Tracking physical activity after total knee arthroplasty
IRAS ID
274998
Contact name
Thomas W Wainwright
Contact email
Sponsor organisation
Bournemouth University
ISRCTN Number
18394084
Duration of Study in the UK
1 years, 4 months, 31 days
Research summary
Total knee arthroplasty surgery, also known as total knee replacement, is recognised as a successful procedure. However some patients find recovery more difficult than others. At present there is little evidence on the best type of exercise recovery plan to give patients following surgery. We think it likely that recovery strategies can be targeted more effectively if they take into consideration participant information that can be collected before surgery, such as expectations regarding recovery, pain, and psychological status.
In this study we ask participants undergoing surgery to wear an activity monitor, worn on the wrist like a watch for a week in the month preceding surgery, and then for six weeks following surgery. We will also collect data prior to surgery on:
• ability to do everyday tasks (using a validated questionnaire);
• functional tests (40m walking test, climbing 9 steps, and number of times participant can do sit-to-stand in 30s);
• pain levels measured on visual analogue scale;
• analgesic use;
• inflammation using level of C-reactive protein in blood (measured again day following surgery)
• pre-operative characteristics –socioeconomic data; expectations of surgery and pain; mental health status; frailty level; number of falls in last 3 months
• osteoarthritis classification (measured on routine x-rays)
Participants will be rung once a week following surgery to record their pain level and analgesic use, and to check they are happy wearing the activity monitor. At six weeks, data will again be collected on the ability to do everyday tasks; functional tests; analgesic and resource use and pain.
In the analysis, changes in the primary outcome measure of activity over time, and distinct subtypes amongst TKA recovery trajectories will be examined using statistical modelling.REC name
North of Scotland Research Ethics Committee 2
REC reference
20/NS/0035
Date of REC Opinion
2 Mar 2020
REC opinion
Favourable Opinion