Toward a Social-Genetic Model of Well-being and Prosociality

  • Research type

    Research Study

  • Full title

    Toward a Social-Genetic Model of Well-being and Prosociality

  • IRAS ID

    125052

  • Contact name

    Aleksandr Kogan

  • Contact email

    ak823@cam.ac.uk

  • Sponsor organisation

    University of Cambridge, Research Operations Office

  • Research summary

    Previous research on the rs53576 SNP of the oxytocin receptor gene (OXTR) has been broadly linked to well-being and prosociality. In particular, individuals with two copies of the G version of the gene have been found to have higher well-being and be more prosocial than individuals with at least one copy of the A version of the gene. Yet research on oxytocin and the oxytocin receptor gene has recently demonstrated that more oxytocin is not always better—instead, situational and personality factors related to social engagement moderate the effects.
    Build upon this foundation, I will conduct two studies to investigate whether two social factors related to social engagement—namely, attachment and self-construal—moderate the impact of the oxytocin receptor gene on a broad array of tasks and questionnaires related to well-being, prosociality, personality, and social functioning.
    Furthermore, the studies will also investigate several other genes implicated in well-being and prosociality—such as genes regulating the serotonin, dopamine, and androgen systems (e.g., Chen et al., 2012). These analyses will be more exploratory in nature, but I am in particular interested in how these genes interact with the oxytocin receptor gene, attachment, and self-construal in predicting well-being, prosociality, personality, and social functioning.

  • REC name

    East of England - Cambridgeshire and Hertfordshire Research Ethics Committee

  • REC reference

    13/EE/0127

  • Date of REC Opinion

    22 May 2013

  • REC opinion

    Further Information Favourable Opinion