TIN-TIN Biobank (Renewal)

• Research type

  Research Tissue Bank

• IRAS ID

  347740

• Research summary

  Transplantation, Immunology and Nephrology Tissue and information Nexus (TIN-TIN)

• REC name

  London - Bromley Research Ethics Committee

• REC reference

  25/LO/0063

• Date of REC Opinion

  27 Feb 2025

• REC opinion

  Favourable Opinion

• Data collection arrangements

  We have stored samples from human peripheral blood obtained from living healthy donors that are completely anonymised and from kidney transplant recipients and their donors that have specific consent for specific research studies. These samples are originated from blood and urine.
  We also have a number of stored frozen cells originated from spleens of deceased donors. These were originated from discarded tissue after use by diagnostic laboratory team in the work up of the transplant.
  Patient samples were always obtained in the course of ethically approved research projects.

  Samples are all stored within the 5th Floor SIMS (School of Immunology and Microbial science) Southwark and Bermondsey Wings, within the faculty of Life Science and Medicine, Guy's Campus.
  

• Research programme

  The TIN-TIN Biobank sits within SIMS (School of Immunology and Microbial science),faculty of Life Science and Medicine, Guy's Campus, based at King's College London. Project aims are to generate high quality biomarker data to enable disease prediction, risk stratification and personalised medicine. The biomarker research team is working on a programme of early post-transplant monitoring to detect acute rejection before clinical warning signs are evident. The programme includes research studies examining clinical utility of biomarkers that associate with long term acceptance of kidney or liver transplants with little or no immunosuppressive therapy. A further study is looking at late post transplant markers which may indicate progressive transplant loss.

• Storage license

  12521

• RTBTitle

  Transplantation, Immunology and Nephrology Tissue and information Nexus (TIN-TIN)

• Establishment organisation

  King's College London

• Establishment organisation address

  Guy's Campus

  Great Maze Pond

  London

  SE1 9RT