Timing ability in Alzheimer's disease FINAL 1.0
Research type
Research Study
Full title
Timing ability as an early cognitive signature of Alzheimer's disease
IRAS ID
204809
Contact name
Charlotte Bonardi
Contact email
Sponsor organisation
University of Nottingham
Duration of Study in the UK
1 years, 11 months, 30 days
Research summary
The overarching aim of this study is to improve the methods for the early diagnosis of Alzheimer's disease. Currently drug treatments are limited in their effectiveness because it is not possible to diagnose AD with any certainty until the clinical symptoms are already quite severe. The aim of this study is to evaluate a computer task that we believe, on the basis of our previous work, will help discriminate Alzheimer's disease from other dementias, mild cognitive impairment (MCI), and normal age-related memory decline. If this proves to be the case the task could form part of the battery of diagnostic tests that are administered to diagnose this condition. We will be recruiting patients from Nottingham Memory clinics who have been diagnosed with dementia, based on clinical assessment and brain imaging. The study will be conducted in the School of Psychology at the University of Nottingham, or in the participant's own home, at their convenience. The study comprises a computer-based task, in which the participant is presented with simple auditory and visual stimuli, and must respond by simply pressing a key on the keyboard, such as the space bar, following the instructions provided. There will also be an assessment of cognitive ability on the basis of a commonly used dementia rating scale. The whole study will last around 90-120 minutes.
REC name
East Midlands - Nottingham 2 Research Ethics Committee
REC reference
16/EM/0214
Date of REC Opinion
17 Jun 2016
REC opinion
Further Information Favourable Opinion