Time to death following diagnosis of recurrent oral cavity cancer
Research type
Research Study
Full title
Time to death following diagnosis of recurrent oral cavity cancer
IRAS ID
183490
Contact name
Madan Ethunandan
Contact email
Duration of Study in the UK
0 years, 7 months, 2 days
Research summary
What is the time to death following diagnosis of recurrent oral cancer?
Oral cavity cancer is the most common subtype of head and neck cancer. It is a significant health burden in the public being ranked as the eightieth most frequent cancer worldwide with over 145,000 deaths per year. For patients, it is a very debilitating condition. The major cause of poor survival rates is considered to be the high incidence of loco-regional recurrences. Chemotherapy remains the only option for advanced metastases whenever salvage surgery or re-irradiation is not feasible but this is associated with a poor prognosis and cure is rare. Therefore, more research on the prognosis of recurrent oral cancer is needed and establishing prognostic factors.
The aim of the proposed project is to provide more information on the prognosis of recurrent oral cancer and look into how patient management can be improved. More precisely, the analysis would involve investigating whether there are any differences following various modalities of cancer treatment. It would be fourth year medical student research with no patient contact because it is a retrospective case-note review of deceased patients with recurrent oral cavity cancer.
It will be conducted at the Southampton General Hospital which has a head & neck cancer database put together following head & neck cancer MDT meetings. The inclusion criteria would be patients who were diagnosed with recurrent oral cavity cancer and death certificate attributed to oral cancer. The following details will be obtained from the database: patient’s age, sex, primary diagnosis, site of lesion, stage of cancer, initial management, time to recurrence, stage of recurrence, management of recurrence and time to death. Data collection is predicted to last for 6 months and there is currently no funding for the research.
REC name
North East - Newcastle & North Tyneside 1 Research Ethics Committee
REC reference
15/NE/0260
Date of REC Opinion
27 Jul 2015
REC opinion
Favourable Opinion