Time-restricted eating (TRE) and protein in older adults
Research type
Research Study
Full title
The effects of time-restricted eating (TRE) with and without additional protein on body composition, muscle function and markers of metabolic health in older adults
IRAS ID
361019
Contact name
Adam Collins
Contact email
Sponsor organisation
University of Surrey
Duration of Study in the UK
1 years, 9 months, 25 days
Research summary
In the UK, more than half of adults aged over 65 are overweight or obese. The high rates of overweight and obesity in this population are associated with a raised risk of non-communicable diseases such as cardiovascular disease and some cancers, and a lower quality of life. At the same time, age-related adverse metabolic changes such as a decline in muscle mass and function (sarcopenia), lower efficiency in nutrient utilization and insulin sensitivity, are associated with frailty, loss of mobility and independence, and mortality.
Time restricted eating (TRE) – an eating pattern characterised by an extended fasting window, has emerged as a promising approach for weight loss and metabolic health. However, there is limited research on TRE in older adult populations.
Amongst older adults, an adequate protein intake is crucial to attenuate the progress of sarcopenia. Research suggests that the current recommendation of 0.75g/kg/d is sufficient for lean mass maintenance in older adults who are in a steady state, however, older adults undergoing energy restriction, such as occurs spontaneously during TRE, may have higher protein requirements.
This randomised controlled trial will compare the effects of 8 weeks of TRE with and without additional protein on body composition, muscle function and markers of metabolic health in a sample of generally healthy adults aged over 60. It will also examine whether being allowed a protein ‘snack’ before the 8-hour eating window starts would affect the feasibility and compliance with TRE. Participants will be randomly allocated to one of four groups: control/no intervention, TRE, TRE with additional protein in the afternoon, and TRE with protein ingested in the morning, before the first meal of the day. Body composition and biochemical markers of metabolic health will be measured at baseline and at the end of the 8-week intervention.REC name
South Central - Hampshire B Research Ethics Committee
REC reference
25/SC/0302
Date of REC Opinion
29 Oct 2025
REC opinion
Further Information Favourable Opinion