TICKER Study - Advanced cardiac imaging in cardiomyopathy of CKD
Research type
Research Study
Full title
The Interrogation of the Cardiomyopathy of chronic Kidney disease with advancEd caRdiac Imaging (TICKER)
IRAS ID
243630
Contact name
Alastair, J Rankin
Contact email
Sponsor organisation
NHS Greater Glasgow and Clyde
Clinicaltrials.gov Identifier
Duration of Study in the UK
1 years, 10 months, 29 days
Research summary
Patients with kidney failure have a much higher risk of heart disease compared to people of the same age without kidney failure. The reason for this is not fully understood. In this project we will use Cardiac MRI (CMR), which is a very detailed scan of the heart and blood vessels, to try to better understand the cardiovascular changes that occur in kidney failure. We will perform CMR scans in 30 patients before and after dialysis (a treatment for patients with kidney failure) to see whether dialysis changes the heart muscle. The same patients will also undergo another type of heart scan, called a CT scan. This will allow us to compare the pictures from the 2 different types of scan to help us better understand any damage to the heart muscle that is present. Finally, we will test a new way to measure hardening of blood vessels on CMR. This study will help us to better understand the heart and blood vessel changes that happen in kidney failure. This research will also be useful for patients without kidney failure. We hope to be able to use it in the future to see which new treatments might be able to reduce the risk of heart disease in patients with kidney failure.
REC name
West of Scotland REC 1
REC reference
18/WS/0138
Date of REC Opinion
13 Aug 2018
REC opinion
Favourable Opinion