THRIVE trial

  • Research type

    Research Study

  • Full title

    Tailored physiotherapy rehabilitation after revision total hip replacement: a feasibility randomised controlled trial

  • IRAS ID

    340762

  • Contact name

    Erin Hannink

  • Contact email

    erin.hannink@ouh.nhs.uk

  • Sponsor organisation

    Oxford University Hospitals NHS Foundation Trust

  • Duration of Study in the UK

    1 years, 11 months, 31 days

  • Research summary

    Hip replacement surgery is usually a success. However, some people will need another surgery on their hip. This is called revision surgery. After revision surgery, people often need to stay in hospital longer and find it difficult to get back to activities they did before. We know a lot about how to help people recover after their first hip replacement, but we do not know enough about the best way to help recover after revision surgery.

    We want to compare two types of physiotherapy for revision surgery: (a) physiotherapy that a patient would normally have after surgery; and (b) physiotherapy designed around the patient that includes tailored exercise and education. As large trials are expensive, we will first run a small study. We will aim to find out: are we able to get enough people to take part; what to people think about the treatment; and are they likely to stick to it?

    We will include sixty people from NHS hospitals who are about to undergo revision surgery. After surgery, the treatment will be assigned at random. Each person will either get:

    (a) Routine treatment: advice and home exercise programme from a physiotherapist and up to two follow-up appointments, or (b) Tailored physiotherapy programme: a 12-week physiotherapy exercise, walking and education programme with 5-8 follow-up appointments, and at 5 and 7 months after surgery, they will get two follow-up phone calls.

    We will take regular measurements to track participants’ progress, including hip strength, activity level, and quality of life. We will measure before surgery and after (at 4 months and 8 months). We will also talk to participants and physiotherapists to find out about their experience in this trial. We hope our findings will help us plan a larger trial.

  • REC name

    West of Scotland REC 4

  • REC reference

    25/WS/0080

  • Date of REC Opinion

    26 Jun 2025

  • REC opinion

    Further Information Favourable Opinion