Thora-3Di Respiratory Rate Validation

• Research type

  Research Study

• Full title

  Thora-3Di™ Respiratory Rate validation. Thora-3Di™ Structured Light Plethysmography (SLP) vs Capnography

• IRAS ID

  165396

• Contact name

  Rachel Wilson

• Contact email

  rachel.wilson@pneumacare.com

• Duration of Study in the UK

  0 years, 3 months, 1 days

• Research summary

  Respiratory rate (RR) is a vital sign used to monitor clinical condition of a patient. Various devices using different techniques are available to measure RR. One technique, capnography, uses continuous monitoring of expired gases, via a nasal cannula to assess end tidal CO2 concentration. This long-established technique is frequently used for patients in intensive care. Both RR and the shape of the capnogram waveform, which has a wave pattern marked by alternating inspiratory and expiratory phases, are used to help monitor the patient. Clinician Over-scored End Tidal C02 (COSC) waveform (whereby an expert identifies and scores each breath on the waveform and counts the number of breaths per minute) is considered to be a “gold standard” for measuring RR.
  Being able to record RR, without contact or interference with the patient is appealing because it requires minimal patient co-operation, enables measurements even during acute respiratory conditions, and may be more representative of “real life” physiology. Based on a principle originally described in the 1980s, a novel instrument that uses a completely non-contact system based on structured light plethysmography (SLP) has recently been designed by Cambridge University and Addenbrookes NHS Foundation Hospital Trust. The device has been refined with the development of the Thora-3Di by PneumaCare Ltd, Cambridge. A grid of visible light is projected onto the thoraco-abdominal wall and two digital video cameras record changes in the grid pattern due to breathing motion. A waveform is produced, and a numerical output of RR is provided . The present study aims to simultaneously measure tidal breathing with the Thora-3Di and a BCI Capnograph 9004 device to compare the Thora-3Di RR output against that of the gold standard clinician over-scored end-tidal C02 (COSC) and to assess equivalence of the two devices with the aim to establishing the validity of SLP for RR measurement.

• REC name

  East of England - Cambridge Central Research Ethics Committee

• REC reference

  15/EE/0005

• Date of REC Opinion

  9 Feb 2015

• REC opinion

  Further Information Favourable Opinion