Thermal Imaging in Liver Disease, Version 1.0
Research type
Research Study
Full title
Thermal Imaging of the Peripheral Vasculature in Liver Disease
IRAS ID
189169
Contact name
Peter Hayes
Contact email
Sponsor organisation
University of Edinburgh
Duration of Study in the UK
0 years, 6 months, 1 days
Research summary
This is a feasibility study, looking to see if thermal imaging and/or near infrared imaging will be useful in identifying changes in the peripheral circulation in patients with different stages of liver disease.
The aim of this study is to use new and advanced thermal imaging techniques to identify changes in the peripheral circulation (blood vessels of hands and feet) and hand temperature in patients with liver disease. These changes could be used as a non-invasive marker of the severity and progression of liver disease. Thermal imaging would also be used to assess the changes in the peripheral vasculature with the use of terlipressin, a drug used as treament for specific complications of liver disease. Patients with acute or chronic liver disease due to any aetiology would be recruited, along with patients without liver disease as healthy controls. Patients with diseases or on drugs known to affect the peripheral vasculature would be excluded. All studies will be performed in a ward setting in the Royal Infirmary of Edinburgh. The subjects would be required for up to three sessions,each lasting 30 minutes. This session would involve static images being taken, and video images of the hands warming up after being cooled for 30 seconds in water at a temperature of 7 degrees Celsius. If the patient is receiving terlipressin therapy, static images would be taken before, during and after terlipressin therapy.REC name
South East Scotland REC 01
REC reference
16/SS/0006
Date of REC Opinion
27 Jan 2016
REC opinion
Further Information Favourable Opinion