TheraFaec: Therapeutic Components within Faecal Material
Research type
Research Study
Full title
The effect of faecal components on the composition of the intestinal microbiome; identifying potential future faecal-based bioactive therapies.
IRAS ID
316183
Contact name
Richard Horniblow
Contact email
Sponsor organisation
University of Birmingham
Clinicaltrials.gov Identifier
ERN_22-0814 ,
Duration of Study in the UK
3 years, 0 months, 2 days
Research summary
There is increasing evidence that components within faecal material could be useful in treating diseases. We know this as a transplant process named 'Faecal Microbial Transplant' (or FMT) where faecal material is transplanted from a healthy donor to a patient can help treat specific diseases. Such diseases include Inflammatory Bowel Disease, Clostridioides difficile infection and potentially diabetes, amongst others currently being examined. However, we don't know what the components are within the faecal material and how they could be exerting their therapeutic effects. Therefore, the goal of this research is to start to understand this in the lab, by examining what is in faecal material and how these components could be working as a medicine.
REC name
London - Surrey Research Ethics Committee
REC reference
22/PR/0982
Date of REC Opinion
22 Jul 2022
REC opinion
Favourable Opinion