The use CT-perfusion techniques in the evaluation of pseudoprogression
Research type
Research Study
Full title
The use of CT-perfusion techniques in the evaluation of pseudoprogression of glioblastoma multiforme tumours
IRAS ID
154710
Contact name
Kumar Das
Contact email
Sponsor organisation
Research, Development & Innovation Team- The Walton Centre NHS Foundation Trust
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
2 years, 0 months, 0 days
Research summary
This study will use CT perfusion scans to look for changes in the brain following treatment for a brain tumour. It is often difficult to detect changes in the brain that are caused as a result of the treatment effects, for example residual damage following radiosurgery may initially look like the tumour has progressed. Using CT perfusion techniques, additional physiological information relating to the tumour site can be acquired which will assist in the correct treatment management of the patient. It should be noted however that patients do not at present have a CT perfusion examination to assist in monitoring the progress of their tumour surveillance over their course of the patient's treatment, therefore this study would require additional ionising radiation, as the patients are only monitored using MRI perfusion techiques at this time.
REC name
North West - Haydock Research Ethics Committee
REC reference
15/NW/0399
Date of REC Opinion
11 Jun 2015
REC opinion
Further Information Favourable Opinion