The RP Genome Project

• Research type

  Research Study

• Full title

  The UK Inherited Retinal Disease Consortium RP Genome Project

• IRAS ID

  176953

• Contact name

  Graeme Black

• Contact email

  graeme.black@manchester.ac.uk

• Clinicaltrials.gov Identifier

  a1265, University of Manchester grant reference

• Duration of Study in the UK

  2 years, 4 months, 31 days

• Research summary

  New technology is revolutionising our understanding of the genetic causes of eye disease, but it produces large amount of complicated data, and to understand the data properly we need to start working in partnerships.

  This research will involve genetic testing of DNA from patients and their relatives. Children and adults would be recruited and there could also be family members affected, but only those with the condition would be directly recruited. the research will be carried out across a group of four sites, and has three main objectives:

  1. Finding new disease causing genes
  2. Increasing the number of patients we can diagnose
  3. Improved data sharing - We aim to work towards a national database for genetic eye disease

  This will lead to a number of other benefits, including, improving the ways that genetic eye disease is diagnosed and helping to give more people access to genetic testing. Sharing of data will lead to the development of a database of patients with a known genetic cause for their eye disease, making it easier to recruit to future clinical trials, which may in the future include treatments

  The research will also strengthen links with other research active groups working in eye disease, including the UK Eye Genetics Group (EGG), Genomics England Clinical Interpretation Partnerships (GECIPs), and aims to provide a UK hub for this type of research.

• REC name

  Yorkshire & The Humber - Bradford Leeds Research Ethics Committee

• REC reference

  15/YH/0365

• Date of REC Opinion

  30 Sep 2015

• REC opinion

  Further Information Favourable Opinion