The role of medicines in deterioration of health V1
Research type
Research Study
Full title
The role of medicines in deterioration of health in frail older people in primary care V1(Version 1)
IRAS ID
228483
Contact name
Nkiruka Umaru
Contact email
Sponsor organisation
University of Hertfordshire
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
2 years, 0 months, 18 days
Research summary
Frail older people are particularly vulnerable to the untoward effects of medicines due to changes in their body system that come with age. These vulnerabilities to the untoward effect of medicines may result in medicines related problems (MRPs). Unresolved MRPs may lead to clinical decline or deterioration resulting in increased use of health care services such as increased use of accident and emergency, hospital and General practice services. Hence it is important to understand the nature and features of deterioration and the MRPs that are associated with these in primary care.
Aim: To investigate the role of medicines in deterioration of health in frail older people from and within the primary care setting
Objectives: To evaluate and characterise the nature and features of deterioration due to medicines in older people presenting in and from the primary care setting; to identify current interventions used in practice in primary care setting to prevent such deterioration and to explore service providers perception of the practical use and success achieved by these interventions ; to make recommendations to support primary care providers to minimise deterioration due to medicines in frail older people within the primary care setting.
Methods: MRPs will be identified using triggers tools, STOPP/START tool and expert judgement and classified using the Hepler and Strand tool. Deterioration will be identified using the BNF, trigger tool, WHO-UMC tool and expert judgement. It will be classified as onset of sudden acute episode or as clinical decline. Data will be extracted into a data extraction form
Data analysis: Quantitative data will be analysed via SPSS 24 (64-bit) while qualitative data will be analysed thematically via Nvivo 11 Windows (64-bits).
Expected Output: Prevalence of MRPs and Deterioration in frail older people, correlation between deterioration and MRPs, understand the usefulness of available tools
Benefits: Improved care of frail older people through better policy.REC name
East of England - Cambridge Central Research Ethics Committee
REC reference
18/EE/0117
Date of REC Opinion
1 May 2018
REC opinion
Unfavourable Opinion